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논문 기본 정보

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학술저널
저자정보
Yanping Ma (Department of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen University) Jinfen Wang (Department of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen University) Tao Wu (Department of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen University) Bowen Zheng (Department of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen University) Tinghui Yin (Department of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen University) Yufan Lian (Department of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen University) Jie Ren (Department of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen University)
저널정보
대한초음파의학회 ULTRASONOGRAPHY ULTRASONOGRAPHY Vol.43 No.5
발행연도
2024.9
수록면
376 - 383 (8page)
DOI
10.14366/usg.24073

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Purpose: This study compared the efficacy of heat insulation between 5% dextrose and 0.9% saline in radiofrequency ablation (RFA). Accordingly, temperature variations and maximum temperatures were assessed at identical distances and heat field distributions.Methods: Cubes of porcine liver tissue, measuring 10 mm across, were selected to precisely align the ablation boundary with the tissue boundary. An 18-gauge electrode with a 7-mm tip was inserted into each cube (10 per group) in a stainless-steel cup containing 40 mL of 5% dextrose or 0.9% saline. Fixed ablation was performed for 3 minutes using continuous mode at 30 W, simulating the typical thermal environment during thyroid RFA. Real-time temperature measurements were recorded by sensors positioned 0, 1, 3, and 5 mm from the cube’s edge. A comparative analysis was conducted to assess the maximum temperature, temperature variation, and duration of temperatures exceeding 42℃.Results: In both groups, the temperature curve declined with increasing distance from the edge of the ablated tissue. However, 0.9% saline exhibited higher maximum temperatures at 1, 3, and 5 mm compared to 5% dextrose (1 mm: 44.55°C±5.25°C vs. 34.68°C±3.07°C; 3 mm: 39.64°C±2.53°C vs. 29.22°C±2.21°C; 5 mm: 38.86°C±2.14°C vs. 28.74°C±2.51°C; all P<0.001). Considering a nerve injury threshold of 42°C, the 0.9% saline also displayed a greater proportion of samples reaching this temperature and a longer duration of temperatures exceeding it (P<0.05).Conclusion: The heat insulation efficacy of 5% dextrose at 1-5 mm exceeds that of 0.9% saline at identical distances and in a common thermal environment during thyroid RFA.

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