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논문 기본 정보

자료유형
학술저널
저자정보
Ayşegül Efe (Ankara Etlik City Hospital) Merve Cura (Ankara Etlik City Hospital) Yusuf Öztürk (Ankara Etlik City Hospital) Meryem Kaşak (Ankara Etlik City Hospital) Sevde Seçer (Ankara Etlik City Hospital) Deniz Yükse (Ankara Etlik City Hospital)
저널정보
대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience Vol.22 No.3
발행연도
2024.8
수록면
544 - 549 (6page)
DOI
10.9758/cpn.24.1158

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초록· 키워드

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Drug-induced acute dystonia is usually associated with combination therapies of neuroleptics, but rarely with the with drawal or rebound effect of various psychotrops. Very sparse reports have described acute dystonia as a methylphenidate withdrawal (rebound effect), particularly in combination modalities. However, there is no case report or research regard ing acute dystonia related to the withdrawal of the short-acting methylphenidate-immediate release form (MPH-IR) in the case of monotherapy of MPH-IR or a combination with guanfacine. Herein, a pediatric case of recurrent acute dystonia with two separate phenomena, locating orolingual and oromandibular/lower extremities, is presented as a with drawal adverse reaction occurring after abrupt discontinuation of MPH-IR when under a combination therapy with guanfacine. Various options such as anticholinergic agents, re-administrating MPH, or turning to monotherapy from combination modalities, can be suggested in treatment, as well as only hydration may also have the benefit of resolving the symptoms, as in the current case. Practitioners should be aware of all possible adverse effects of MPH, even the rebound effect of short-acting forms.

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