지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.9
- 수록면
- 274 - 285 (12page)
- DOI
- 10.17998/jlc.2024.08.13
이용수
초록· 키워드
오류제보하기
Backgrounds/Aims: The treatment landscape for hepatocellular carcinoma (HCC) has significantly evolved over the past decade. We aimed to analyze trends in treatment patterns for HCC using a nationwide claims database from the Korean Health Insurance Review and Assessment Service.
Methods: This retrospective population-based cohort study analyzed 171,002 newly diagnosed HCC patients between 2008 and 2022. Etiologies and treatment modalities were categorized based on the ICD-10 codes and insurance data.
Results: The annual incidence decreased from 11,814 in 2008 to 10,443 in 2022. However, patients aged ≥70 increased noticeably, with those aged ≥80 rising from 3.8% in 2008 to 13.1% in 2022. From 2008 to 2022, the predominant cause of hepatitis B virus decreased from 68.9% to 59.7%, whereas nonalcoholic fatty liver disease increased from 8.9% to 15.8%. The initial treatment trends shifted: surgical resection and systemic therapy increased from 12.2% to 21.3% and from 0.2% to 9.6%, whereas transarterial therapy decreased from 49.9% to 36.6%. Best supportive care decreased from 31.7% to 21.3%. In the subgroup analysis, laparoscopic resection rate increased from 10.6% to 60.6% among the surgical resections. Sorafenib initially accounted for 100%, lenvatinib peaked at 36.5% in 2021, and atezolizumab-bevacizumab became the most widely used (63.1%) by 2022 among the systemic therapies.
Conclusions: This study demonstrates the temporal changes in the treatment patterns of Korean HCC patients. Surgical resection, particularly laparoscopic liver resection, and systemic therapy has increased significantly. These changes may have been influenced by reimbursement policies and advances in clinical research.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Systemic therapy in advanced hepatocellular carcinoma
Clinical and Molecular Hepatology
2023 .04
-
Impact of Anatomic Liver Resection for Hepatocellular Carcinoma: A Systemic Review And Meta-analysis
대한외과학회 학술대회 초록집
2020 .11
-
Laparoscopic anatomical resection for hepatocellular carcinoma
대한외과학회 학술대회 초록집
2019 .10
-
Liver resection in elderly hepatocellular carcinoma patients (≥ 75 years) is safe
Annals of Hepato-Biliary-Pancreatic Surgery
2021 .12
-
Clinical practice guidelines and real-world practice for hepatocellular carcinoma in Taiwan: Bridging the gap
Clinical and Molecular Hepatology
2023 .04
-
Clinical effectiveness and safety of laparoscopic liver resection versus open liver resection for hepatocellular carcinoma in elderly patients: A systematic review and meta-analysis
Annals of Hepato-Biliary-Pancreatic Surgery
2022 .12
-
Surgical outcomes after robotic liver resection in hepatocellular carcinoma
대한임상종양학회 학술대회지
2022 .02
-
Resection of intermediate stage hepatocellular carcinoma
Annals of Hepato-Biliary-Pancreatic Surgery
2021 .12
-
Realization of improved outcomes following liver resection in hepatocellular carcinoma patients 75 years of age and older
Annals of Hepato-Biliary-Pancreatic Surgery
2022 .12
-
The clinical management of hepatocellular carcinoma in China: Progress and challenges
Clinical and Molecular Hepatology
2023 .04
-
The emerging age-pattern changes of patients with hepatocellular carcinoma in Korea
Clinical and Molecular Hepatology
2023 .01
-
A scoring system to predict the risk of postoperative complications after laparoscopic liver resection in elderly hepatocellular carcinoma patients
Annals of Hepato-Biliary-Pancreatic Surgery
2021 .12
-
Laparoscopic versus open liver resection for hepatocellular carcinoma: Long-term and short-term surgical outcomes depending on tumor size
Annals of Hepato-Biliary-Pancreatic Surgery
2021 .12
-
Laparoscopic versus open anatomical liver resection for hepatocellular carcinoma: A systematic review and meta-analysis
Annals of Hepato-Biliary-Pancreatic Surgery
2022 .12
-
Prognostic factors after resection for large hepatocellular carcinoma over 5cm
한국간담췌외과학회 학술대회지
2016 .04
-
Long-term and perioperative outcomes evaluation of pure laparoscopic liver resection compared with open liver resection for hepatocellular carcinoma with propensity score matching
대한외과학회 학술대회 초록집
2017 .11
-
Hepatocellular carcinoma in children. Liver resection and liver transplantation outcomes
Annals of Hepato-Biliary-Pancreatic Surgery
2021 .12
-
Long-Term Surgical Outcomes of Patient with Hepatocellular Carcinoma Underwent Laparoscopic Liver Resection in Low-Volume Centers: A Case-Controlled Study
대한외과학회 학술대회 초록집
2019 .10
-
Impact of anatomical liver resection for hepatocellular carcinoma: A systematic review and meta-analysis
Annals of Hepato-Biliary-Pancreatic Surgery
2021 .12
-
Clinical usefulness of 18F-FDG PET in patients with hepatocellular carcinoma undergoing surgical resection
Annals of Hepato-Biliary-Pancreatic Surgery
2022 .12
최근 본 자료
댓글(0)
0