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논문 기본 정보

저자정보
(전북대학교) (우석대학교)
저널정보
한국체육과학회 한국체육과학회지 한국체육과학회지 제34권 제5호 (자연과학 편)
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    초록·키워드

    This study investigated the effects of eight weeks of treadmill training with different exercise intensities on the expression of eNOS, nNOS, iNOS, and PGC-1α in the skeletal muscles of aged rats. Twenty eight 72week old male Sprague-Dawley rats were randomly divided into four groups: a sedentary control group and three exercise groups that performed low(15m/min), moderate(20m/min), or high-intensity(25m/min) running, five days per week. After the training period, gastrocnemius muscles were collected, and protein expression levels were quantified using Western blotting. The results showed that the high-intensity group exhibited the greatest increases in eNOS and PGC-1α expression, while nNOS expression reached the highest level in the same group. In contrast, all exercise groups showed a decreasing tendency in iNOS expression compared with the control. These findings suggest that high-intensity aerobic exercise optimally enhances nitric oxide production and mitochondrial biogenesis in the aging skeletal muscle.

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      UCI(KEPA) : I410-151-26-02-094516617