인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
This study evaluated the cardioprotective potential of Caesalpinia bonducella (L.) Roxb. seed extracts in obese rats fed a high-fat diet (HFD), aiming to improve fat metabolism, reduce oxidative stress, and prevent harmful lipid accumulation in blood vessels. Thirty-six adult albino rats were divided into six groups: normal control, HFD control, HFD with simvastatin, and HFD with petroleum ether (PTCB), ethyl acetate (EACB), or ethanolic (ETCB) seed extracts (100 mg/kg) for 30 days. Body weight, lipid profile (total cholesterol, LDL, HDL, triglycerides), and oxidative stress markers (catalase and malondialdehyde) were measured. EACB and ETCB extracts significantly lowered total cholesterol, LDL, triglycerides, and malondialdehyde while increasing HDL and catalase, with ETCB showing superior effects. The extracts also reduced HFD-induced weight gain, indicating improved fat metabolism. These results suggest that C. bonducella seed extracts, particularly ETCB, protect against atherosclerosis and oxidative stress, supporting their potential as natural cardioprotective agents and warranting further studies to clarify their underlying molecular mechanisms.
본문·목차
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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UCI(KEPA) : I410-151-26-02-095629364