인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.6
- 수록면
- 52 - 61 (10page)
이용수
초록· 키워드
dose-dependent manner when TS was increased from 1.0 mg/ml to 4.0 mg/ml (p<0.05). After administration of 0.1 ml of TS (32 mg/ml) in the rat, the bladder pressure was 37.5±8.5 mmHg at 52.1±7.0 sec. during isovolumetric bladder contraction, showing no significant differences from 35.7±7.8 mmHg and 50.7±7.2 sec, respectively, before treatment. However, when 0.1 ml of TS (32 mg/ml) was administered, the relative reduction of urethral pressure was 6.9±0.5 mmHg at 62±7.5 sec, which was significantly higher compared to 4.6±1.1 mmHg at 45±10 sec before treatment (p<0.05). For the cavernosal injection study, the change in intracavernosal pressure (△ICP) was examined after administering 0.1 ml of TS. The cumulative additions of TS at concentrations from 0.5 mg/ml to 32 mg/ml increased △ICP from 1.3±0.5 to 21.3±7.8 mmHg in a dose-dependent manner (p<0.05). The duration of tumescence was from 0.3±0.1 to 5.2±0.2 min, showing dose-dependent increase (p<0.05).
Furthermore, the cumulative addition of TS at concentrations from 0.5 mg/ml upto 32 mg/ml did not cause any significant change in systemic blood pressure.
Conclusion: These results suggest that ginseng improves voiding functions, which is mainly achieved by TS relaxing the proximal urethra, the most important part of the bladder outlet function. In addition, ginseng safely induced a penile erection hemodynamically by relaxing the corpus cavernosum.
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