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Wiley Microbial Biotechnology 16(5)
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    초록·키워드

    This paper reviews bacterial cellulose production, with a focus on biocomposites that have antimicrobial and antibiofilm effects. This page is a compendium of abstracts representing books, chapters and articles related to bacterial cellulose. This review covers the production of bacterial cellulose with a focus on scale-up to industrial-scale production. Given the commercial interests in bacterial cellulose, both conventional methods and synthetic biology approaches are being used. This report describes what it calls “engineered living materials” which are fabricated from millimeter-sized cellulose spheroids from cultures of Komagataeibacter rhaeticus. This paper makes the point that bacterial cellulose is considered to be “generally regarded as safe,” or GRAS, making it useful for food or medical applications. It also has utility for its properties of gel formation, emulsifying properties and water retention. This is one of the early reports describing the stimulation of bacterial cellulose synthesis by the signaling molecule cyclic di-GMP. This site contains the coordinates for BcsB that comprises most of the approximately one megadalton Bcs cellulose synthase complex. This structure and the accompanying paper describe snapshots along the pathway of cellulose synthesis and its translocation to the exterior of the cell. The protein system was expressed in Escherichia coli but originated from Cereibacter sphaeroides. Komagataeibacter hansenii ATCC 53,582 is important commercially because it produces cellulose in relatively high yield. This study looked into some of the enzyme complexes in cellulose biosynthesis and the networks involved in its regulation.

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