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Elsevier BV JAAD Case Reports 39
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    COVIDe19-associated diffuse dermal angiomatosis managed with pentoxifylline and topical timololTo the Editor: We appreciate the article from Young et al, 1 which described gestational gigantomastia as a risk factor for diffuse dermal angiomatosis (DDA), allowing us to introduce another unreported risk factor and treatment options.DDA is a cutaneous reactive angiomatosis presenting as reticulated erythematous-to-violaceous plaques with ulceration.DDA of the breasts (DDA-B) typically occurs in middle-aged women with the following risk factors: obesity, large pendulous breasts, smoking, hypertension, and vasculopathy. 2Macromastia coupled with vaso-occlusive conditions or hypercoagulability leads to prolonged ischemia and reactive vascular proliferation. 3 DDA-B after COVID-19 has not been reported.We present a case of DDA-B after COVID-19 infection and suggest adding topical timolol to the therapeutic armamentarium.A 39-year-old woman, unvaccinated against COVID-19, with a high body mass index (64.01kg/ m 2 ), and size ''M'' bra-cup presented with a 2-month history of painful rash affecting both breasts.

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