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Wiley Physiological Reports 12(1)
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    초록·키워드

    Swimmer athletes showed a decreased ventilatory response and reduced sympathetic activation during peripheral hypoxic chemoreflex stimulation. Based on these observations, we hypothesized that swimmers develop a diminished cardiorespiratory coupling due to their decreased hypoxic peripheral response. To resolve this hypothesis, we conducted a study using coherence time-varying analysis to assess the cardiorespiratory coupling in swimmer athletes. We recruited 12 trained swimmers and 12 control subjects for our research. We employed wavelet time-varying spectral coherence analysis to examine the relationship between the respiratory frequency (R<sub>f</sub> ) and the heart rate (HR) time series during normoxia and acute chemoreflex activation induced by five consecutive inhalations of 100% N<sub>2</sub> . Comparing swimmers to control subjects, we observed a significant reduction in the hypoxic ventilatory responses to N<sub>2</sub> in swimmers (0.012 ± 0.001 vs. 0.015 ± 0.001 ΔV<sub>E</sub> /ΔVO<sub>2</sub> , and 0.365 ± 0.266 vs. 1.430 ± 0.961 ΔV<sub>E</sub> /ΔVCO<sub>2</sub> /ΔSpO<sub>2</sub> , both p < 0.001, swimmers vs. control, respectively). Furthermore, the coherence at the LF cutoff during hypoxia was significantly lower in swimmers compared to control subjects (20.118 ± 3.502 vs. 24.935 ± 3.832 area under curve [AUC], p < 0.012, respectively). Our findings strongly indicate that due to their diminished chemoreflex control, swimmers exhibited a substantial decrease in cardiorespiratory coupling during hypoxic stimulation.

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