인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Magnetic resonance elastography (MRE) is a noninvasive brain stiffness mapping method. Ultrasound-based transtemporal time-harmonic elastography (THE) is emerging as a cost-effective, fast alternative that has potential applications for bedside monitoring of intracranial pressure. We aim to investigate the accuracy of THE in comparison to MRE performed in the brain. Ten healthy volunteers (25-40 years old) underwent multifrequency MRE (20-35 Hz) and THE (27-56 Hz). Fiducial-marker-based optical tracking of the ultrasound field of view was used to align THE to 3D MRE. THE- and MRE-derived shear wave speed (SWS) was determined as a measure of brain stiffness and averaged within regions of various depths for cross-modality correlation analysis. MRE-measured SWS ranged from 1.0 to 1.3 m/s and was negatively correlated with age (R<sup>2</sup> = 0.44, p = 0.035). After registration of both modalities, SWS values were linearly correlated (MRE: 1.14 ± 0.08 m/s, THE: 1.13 ± 0.10 m/s; R<sup>2</sup> = 0.62, p = 0.007). Best agreement between modalities was achieved at depths of 40-60 mm, suggesting this range provides a viable trade-off between ultrasound attenuation and near-field bias. Similar brain regions can be consistently measured with both elastography modalities, despite the regional and individual variations of stiffness. Transtemporal THE yields stiffness values in a range similar to those obtained with more expensive MRE.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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