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EDP Sciences BIO Web of Conferences 143
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    초록·키워드

    Vibriosis, caused by various Vibrio species, poses a significant challenge in the aquaculture of Litopenaeus vannamei . Bacteriophages present a promising biocontrol option due to their ability to specifically target and kill bacteria without harmful side effects. This study evaluates the effectiveness of bacteriophages isolated from shrimp intestines and mangrove sediment in controlling Vibrio infections in L. vannamei. Using a Completely Randomized Design (CRD) with five treatment groups and four replications, including control, pathogen-exposed, and various phage treatments, the research found that purified bacteriophages, especially those from shrimp intestines (26 × 10 9 PFU/mL), significantly inhibited bacterial growth in vitro. In vivo, phage-treated shrimp showed improved immune responses and higher survival rates than controls. Although total hemocyte counts remained unchanged, increased phagocytic activity suggests that phage therapy could be an effective and sustainable method for managing Vibrio infections in shrimp farming.

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