인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract Background Inflammatory Bowel Diseases (IBD) are the gastro-intestinal diseases of the current century. They are described by alternating periods of activity & remission. The assessment of severity is classically done by scoring systems for each disease which depend on patients’ symptoms, inflammatory markers, endoscopic findings, and disease impact on functional activities. The current study focused on some of the potentially modifiable risk factors for activity, not involved in classic scoring systems like sarcopenia & Prognostic Nutritional Index (PNI) in a group of IBD studied cases. Results A prospective study on 146 patients with established diagnosis of IBD; divided into two groups; Group1 were studied cases in activity; and Group 2 were patients in remission. Both groups were subjected to clinical assessment, laboratory tests, endoscopies, cross-sectional imaging with specific attention to psoas muscle indices. Both groups were followed up clinically for at least 6 months by clinical activity scores. In this research, the mean patients’ age was 35 years and 45% were females; the prevalence of sarcopenia in studied cases with active IBD had been 49.3% & 6.8% in remission. It was more prevalent in Crohn’s disease. Sarcopenia and low PNI were significantly related to disease activity, & poor clinical outcome in studied cases with IBD with a p - value < 0.05. Conclusion Sarcopenia and low PNI can be used as markers of activity of IBD. They are associated with worse outcomes. It is recommended to early detect and manage sarcopenia and malnutrition in IBD patients to improve outcomes.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.