인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
The subjective experience of self-awareness is attributed to the human capacity for introspective thought during periods of mind-wandering. However, how this cognitive function is impacted in individuals with mild cognitive impairment (MCI) still needs to be better understood. To address this gap, we investigated alterations in self-referential thinking in a cohort of 30 MCI patients, comparing them to 60 healthy old-aged and 60 healthy younger controls. MCI patients exhibited a notable decline in overall cognitive function, as evidenced by significantly lower scores on the Montreal Cognitive Assessment (MoCA), with particular deficits in Memory subscore and Memory Index Score (MIS). Employing the Amsterdam Resting-State Questionnaire (ARSQ) to assess mind-wandering, we observed diminished self-related thoughts relating to personal past experiences and future thinking among MCI patients. Notably, using high-density electroencephalography (hdEEG) microstate analysis, we detected reduced neural activity for microstate C associated with self-related thoughts in MCI patients and healthy older relative to healthy younger controls, and an increase in neural activity for microstate A in MCI patients compared to healthy older and younger controls. This aberrant temporal activity was localized within brain regions implicated in episodic autobiographical memory and the default mode network. Our results highlight a link between impaired mind-wandering ability and dysfunction within the intrinsic neural networks of MCI patients, underscoring its implications for disruptions in the sense of self within this clinical population.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
최근 본 자료 전체보기
