인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Sheep casein and whey proteins, α-lactalbumin, β-lactalbumin, and β-lactoglobulin 1/B, are good sources of bioactive peptides that have potential health benefits including antimicrobial, antioxidant, antihypertensive, and immunomodulatory activities. The following paper discusses the in-silico analysis of these proteins retrieved from the UniProtKB database, with emphasis on their amino acid compositions and the bioactive peptides formed after hydrolysis with pepsin and trypsin. Their physicochemical properties, bioactivity, and allergenicity were determined by the use of sophisticated bioinformatics tools. One of the interesting findings includes their inhibition activity against dipeptidyl peptidase IV, which might be of great importance in the management of type 2 diabetes. The allergenicity predictions where a mixed bag as some peptides had the potential to be flagged as allergens due to the similarities in their sequence with the proteins in bovine milk. Others were predicted to be nonallergenic and safer for further use. The results suggest that bioactive peptides from sheep could potentially be used in food and pharmaceutical applications, although the need for further experimental validation, especially on safety, is critical. In-silico approaches provide an efficient and cost-effective means for screening peptides.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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