인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract Background This study was carried out aiming to: 1. Assess the prognostic role of the clinical as well as ultrasound (US) measures of inflammation for predicting the risk of relapse, and the need for adjunctive biologic therapy. 2. Evaluate the rapidity and sensitivity to change of US measures in the initial months following the diagnosis and initiation of treatment of GCA. 3. Stratify Giant Cell Arteritis (GCA) patients according to their risk of relapse and the possibility of early prediction and classification of the individual subject. This was based on a prospective follow up study which included 67 GCA patients diagnosed according to the EULAR/ACR classification criteria and monitored for 12-months period. Results Ultrasound OMERACT ultrasonography score for giant cell arteritis (OGUS) scores significantly improved between baseline and 4 weeks ( P = 0.001) and the improvement was persistent from 2–12 months ( P = 0.01) in non-relapsing patients, whereas negative changes in the OGUS scores, as early as 8-12-weeks of therapy, in comparison to the baseline or last assessment visit, were an early predictor of relapse. Negative changes in the patient’s functional ability and worsening of the disease activity score were also predictors of relapse ( p < 0.001). Conclusion The extent and severity of GCA disease assessed and monitored by health-related quality of life measure, disease activity status as well as ultrasound measures have a prognostic role. US is a useful tool for monitoring GCA disease activity and in association with other conventional biomarkers and disease activity score, they can predict the disease relapse.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.