인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
The combined impact of physical activity (PA), diet quality, and their change over time on cardiometabolic disease risk remains uncertain. We aimed to examine the associations between the combined trajectories of these health behaviours and the incidence of diabetes mellitus (DM) and cardiovascular diseases (CVD) among 9,276 middle-aged adults. In the EPIC-Norfolk study, longitudinal changes in PA energy expenditure (∆PAEE) and Mediterranean diet score (∆MDS) were derived from repeated measurements between 1993 and 2004. Over a median follow-up of 18 years, 968 participants developed DM and 2,540 developed CVD by 2022. In mutually adjusted Cox regression models, HR (95%CI) per 1-SD higher ∆PAEE and ∆MDS were 0.87 (0.81-0.94) and 0.92 (0.86-0.99) for incident DM, and 0.94 (0.89-0.99) and 0.93 (0.88-0.97) for incident CVD, respectively. Compared to participants with sustained low PAEE and MDS, those with sustained higher levels of both traits had a 40% (21-55%) lower incidence of DM and a 25% (11-37%) lower CVD incidence. At the population level, consistent favourable levels of activity and diet quality could reduce cumulative incidence of DM by 22% and CVD by 16%. The greatest benefit arises when an active lifestyle is combined with a high-quality diet, initiated earlier in adulthood, and maintained over time.
#Medicine
#Incidence (geometry)
#Diabetes mellitus
#EPIC
#Metabolic equivalent
#Cumulative incidence
#Demography
#Mediterranean diet
#Population
#Proportional hazards model
#Physical activity
#Internal medicine
#Epidemiology
#Gerontology
#Endocrinology
#Physical therapy
#Environmental health
#Cohort
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