인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Even though acute pain comes in many different shapes and forms, a lot of experimental pain studies predominantly employ cutaneous heat pain. This makes a comparison between different pain types and the link between findings from these experimental studies to clinical pain difficult. To bridge this gap, we investigated both cuff pressure pain and cutaneous heat pain using a within-subject design in combination with functional magnetic resonance imaging (fMRI). Noxious stimuli were applied with a 17-s duration at three different intensities above the pain threshold using a thermode and a computer-controlled cuff pressure device. Both pain modalities led to contralateral activation in the anterior insula and parietal operculum. Heat pain showed greater activation in the precentral gyrus, pontine reticular nucleus, and dorsal posterior insula, whilst pressure pain showed greater activation in the primary somatosensory cortex and bilateral superior parietal lobules. Most importantly, the time course of the fMRI signal changes differed between modalities, with pressure pain peaking in the first stimulus half, whereas heat pain led to a prolonged and increasing response across the stimulus duration with a peak in the second stimulus half. Our findings suggest that pressure and heat pain lead to common as well as different (temporal) activation patterns in key pain processing regions.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.