인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Anorexia nervosa (AN) is a severe mental disorder, and patients with AN are characterized by a low body weight and a fear of gaining weight. Restoration of body weight to the normal range is one major treatment aim, which can be a challenging process for the patients. Hence, as a psychopathological symptom of AN, weight manipulations such as water loading before weighing are commonly observed in clinical routine. Biological impedance analysis (BIA) is a helpful tool in routinely visualizing changes in body composition during the refeeding process. Here, we targeted the question whether BIA could potentially detect water loading in healthy, young and normal weight women serving as a preclinical model for patients with AN.Sixty-one women (mean ± SD, 22.2 ± 2.2 years, 20.4 ± 1.0 kg/m<sup>2</sup>) were included in the analyses. We used a full experimental setting with a cross-over design on two consecutive days. On both days, all participants underwent a baseline BIA in the fasting state (t<sub>0</sub>). Directly thereafter, participants either consumed 1000 ml of tap water (intervention-condition) or waited for the second BIA measurement 20 min (t<sub>1</sub>) after baseline (control-condition), and vice versa the subsequent day. Two further BIA measurements took place at 40 (t<sub>2</sub>) and 60 min (t<sub>3</sub>) after baseline.After water consumption, we found increases in derived fat mass (FM) and phase angle at t<sub>1</sub> to t<sub>3</sub>, decreases at t<sub>1</sub> and subsequent increases at t<sub>2</sub> and t<sub>3</sub> in extracellular water (ECW) and total body water (TBW). In contrast, skeletal muscle mass (SMM) and ECW/TBW remained rather stable. In the control-condition, most parameters remained constant.Our study provided insight into the changes of impedance raw data and derived body compartments after water consumption among young, healthy and normal weight women. Although the considerable increase of FM in combination with a rather stable course of SMM, as found in our experiment after the consumption of water, could be a potential hint for water loading, further investigation considering the limitations of the present study as for instance the different metabolisms of patients with AN vs. healthy women is required, before transferability to the clinical setting will be given.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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