인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
"Predicted brain age" refers to a biomarker of structural brain health derived from machine learning analysis of T1-weighted brain magnetic resonance (MR) images. A range of machine learning methods have been used to predict brain age, with convolutional neural networks (CNNs) currently yielding state-of-the-art accuracies. Recent advances in deep learning have introduced transformers, which are conceptually distinct from CNNs, and appear to set new benchmarks in various domains of computer vision. Given that transformers are not yet established in brain age prediction, we present three key contributions to this field: First, we examine whether transformers outperform CNNs in predicting brain age. Second, we identify that different deep learning model architectures potentially capture different (sub-)sets of brain aging effects, reflecting divergent "concepts of brain age". Third, we analyze whether such differences manifest in practice. To investigate these questions, we adapted a Simple Vision Transformer (sViT) and a shifted window transformer (SwinT) to predict brain age, and compared both models with a ResNet50 on 46,381 T1-weighted structural MR images from the UK Biobank. We found that SwinT and ResNet performed on par, though SwinT is likely to surpass ResNet in prediction accuracy with additional training data. Furthermore, to assess whether sViT, SwinT, and ResNet capture different concepts of brain age, we systematically analyzed variations in their predictions and clinical utility for indicating deviations in neurological and psychiatric disorders. Reassuringly, we observed no substantial differences in the structure of brain age predictions across the model architectures. Our findings suggest that the choice of deep learning model architecture does not appear to have a confounding effect on brain age studies.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.