인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
No data exist comparing racial differences in bone microstructure or mechanical competence using HR-pQCT and micro-finite element analysis (μFEA) in elderly Hispanic, non-Hispanic Black (NHB), and non-Hispanic White (NHW) men. These modalities were utilized to investigate skeletal health in 255 elderly men (age ≥ 65) from a population-based study in New York City: 40.0% Caribbean Hispanic (CH), 35.3% NHW, and 24.7% NHB. Covariate-adjusted (age, BMI, calcium consumption, smoking, diabetes, liver disease, and HIV) results are shown. We also explored the effect of socioeconomic (SE) factors. At the distal tibia, CH men had lower trabecular indices with 9% lower stiffness and failure load (both <i>p</i> < .05) compared to NHW. CH men had smaller cortical area (Ct.Ar) and lower thickness (Ct.Th) compared to NHB, with 11% (<i>p</i> < .05) lower stiffness and failure load. After adjusting for SE, differences in stiffness and failure load between CH and NHW were no longer significant. Comparing NHB to NHW men at the tibia, NHB had lower trabecular indices but greater Ct.Ar, Ct. volumetric bone density (Ct.vBMD) and Ct.Th, with no differences in stiffness and failure load. At the diaphyseal tibia, Ct.Ar and Ct.Th were lower in CH compared to both NHW and NHB men, with 11% and 17% lower stiffness and failure load compared to NHW and NHB (all <i>p</i> < .05). Radial μFEA indices were not different. In conclusion, CH elderly men have lower mechanical competence at the tibia compared to NHW and NHB men, which could result in a greater risk of incident fracture in CH men. Some differences between CH and NHW may be related to modifiable SE factors. Studies assessing HR-pQCT's ability to predict incident fracture and how SE factors affect fracture risk are needed in men of races and ethnicities historically underrepresented in skeletal research.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.