인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Eosinophils are a part of the human immune system and have traditionally been thought to be associated with allergic reactions. Recent research has revealed their potentially important role in cardiovascular disease. We retrospectively collected data on 1155 patients who were diagnosed with carotid artery stenosis at our center from January 2016 to June 2021. These data included demographic information, laboratory measurements, and carotid ultrasounds. We constructed predictive models through binary logistic regression. A total of 1,155 patients were ultimately included in this study, among whom 157 experienced major adverse cardiovascular and cerebrovascular events (MACCE) within a three-year follow-up period. Multifactorial adjustment showed that previous operation history (OR 1.66[1.14-2.41], P = 0.008), previous history of stroke (OR 1.59[1.10-2.31], P = 0.014), total proteins (OR 0.97[0.95-0.99], P = 0.02), erythrocyte sedimentation rate(OR 1.01[1.01-1.02], P = 0.031), eosinophil counts(OR 4.62[1.60-13.35], P = 0.005) and treated with calcium channel blockers(CCBs) + β-blockers(BBs) (OR 3.08[2.04-4.63], P < 0.001) were independently associated with 3-year MACCE. Based on these key factors, the prediction model we constructed demonstrated satisfactory prediction performance, with an initial value of 0.739 for the area under the curve, which was stabilised at 0.721 after adjustment. After a dichotomous analysis of eosinophils based on cut-off values, we assessed their role in different outcomes. The results of the analysis showed that eosinophil counts was a significant risk factor for all the outcomes considered. Patients with carotid artery stenosis exhibiting a baseline eosinophil counts of 0.185*10<sup>9</sup>/L had a higher incidence of MACCE. Furthermore, a previous 3-year operation history, previous history of stroke, total proteins, erythrocyte sedimentation rate and treated with a combination of CCBs and BBs were also significantly associated with the occurrence of MACCE.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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