인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Viral infections and reactivations have been linked to several pregnancy complications. Antiviral medications are often prescribed as a prophylactic measure to prevent infant infection. This study examines associations between antiviral medication use during pregnancy and preeclampsia, thereby exploring links between viruses and such pregnancy complication. We analyzed data from 618,814 first-time mothers in Sweden (2007-2019) using four national registers. Of these 27,135 (4.4%) developed preeclampsia and 18,004 (2.9%) filled an antiviral medication prescription. Adjusted logistic regression with inverse probability of treatment weighting was used to evaluate associations between use of antiviral medication and preeclampsia. Antiviral medication use was associated with a reduced likelihood of preeclampsia (aOR 0.88; 95% CI, 0.81-0.96). Particularly, antiviral medication use was associated with a reduced likelihood of developing preeclampsia with delivery before 34 weeks gestation (aOR 0.66; 95% CI, 0.48-0.92) and preeclampsia with a small for gestational age infant (aOR, 0.74; 95% CI, 0.57-0.96). Timing of antiviral prescription filling was also investigated. Antiviral medication use in the third trimester was associated with a reduced likelihood of preeclampsia (aOR 0.77; 95% CI, 0.67-0.90), but not when used during the first two trimesters. Our study suggests that viral infections or reactivation might play a role in the etiology of preeclampsia, highlighting the need to further explore viral infections' role in preeclampsia development.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.