인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract This study aimed to develop PEGylation based nanoparticles using garlic essential oil (GEO) and polyethylene glycol (PEG) by melt-dispersion method. Physico-chemical characteristics of GEO loaded PEG nanoparticles (GPNs) was analysed by Differential Scanning Calorimetry (DSC), Dynamic Light Scattering (DLS), and Gas Chromatography (GC) techniques. Optimized GPN was subjected to stability and physico-chemical characteristics analysis up to six-month storage. Then, insecticidal potentiality of GPN was investigated and microstructural impacts on the beetle surface was observed under Scanning Electron Microscopy (SEM). Among the developed GPNs, DLS characteristics revealed GPN4 as optimal with 195.90 nm of particle size, 0.25 PDI, and 86.48% of encapsulation efficiency. Significantly, there was no physico-chemical changes on GPN4 during six-month storage compared to control. In GC analysis, diallyl sulfide, diallyl disulfide, and diallyl trisulfide were detected as major constituents of GEO and GPN4. The GPN4 showed potential contact toxicities against Sitophilus oryzae , Rhyzopertha dominica , and Tribolium castaneum adults with 165.73, 169.95, and 192.82 ppm of LC 50 values at 72 h exposure. SEM observations exhibited adhesion of powder-form nanoparticles and abrasions on the cuticular surface of beetles. In conclusion, the study results suggested that GPN4 was a stable and potential contact toxicant, which could be useful as nano-protectant against stored-product beetles.
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