인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract Background Cystic fibrosis is an autosomal recessive disease that occurs due to a mutatioxn of the cystic fibrosis transmembrane conductance regulator protein, resulting in aberrant ion transport and dehydration of the epithelial surface lining, which causes thick mucus buildup, persistent inflammation, and recurring infections, ultimately causing tissue damage and remodeling. Weak respiratory muscles and insufficient lung compliance are causing dyspnea. About 75% of respiratory motions are produced by the diaphragm, and the distance it may travel in a respiratory cycle is known as diaphragmatic excursion. The study aimed to detect the role of ultrasound as an easy, non-invasive technique to evaluate pediatric cystic fibrosis patients’ diaphragmatic thickness and excursion and its correlation to pulmonary function tests. Results The diaphragmatic thickness in the patient group ranged from 1.1 to 5.3 mm with a lower median of 2.3 mm, diaphragmatic excursion in tidal breathing ranged from 1.5 to 8.7 mm with a lower median of 3.5 mm, and diaphragmatic excursion during deep inspiration ranged from 3 to 18 mm with lower median 7.2 mm compared to the control group, which had medians of 4.3 mm, 7.2 mm, and 14.7 mm, respectively. The diaphragmatic thickness and excursion positively correlated with forced expiratory volume in 1 s, forced vital capacity, and oxygen saturation, while inversely correlated with dyspnea score. Conclusion Ultrasound is a safe, simple, and noninvasive bedside method that can help clinicians assess diaphragmatic excursion and thickness in pediatric cystic fibrosis patients and correlates with pulmonary function tests.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.