인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract Background In patients undergoing hemodialysis, serum blood urea nitrogen (BUN) and creatinine (Cr) levels are affected by factors such as diet and muscle mass. Few studies have examined the optimal range of serum BUN/Cr ratios in these patients. Therefore, this study examined the association between the BUN/Cr ratio and all-cause mortality. Methods This retrospective cohort study evaluated pre-dialysis BUN/Cr ratios. Cox regression analysis was performed with all-cause mortality as the outcome and the BUN/Cr ratio as an explanatory factor. Results This study included 1321 patients undergoing hemodialysis (mean age: 63.5 ± 11.7 years; dialysis duration: 110 [17–203] months; 70.0% male). The mean serum BUN was 65.1 ± 14.1 mg/dL, Cr was 11.5 ± 3.1 mg/dL, and BUN/Cr ratio was 5.97 ± 2.26. During the study, 253 deaths occurred. Using the group with the second-lowest serum BUN/Cr ratio (4.7–5.6) as a reference, the highest BUN/Cr ratio (> 6.8) was associated with a significantly higher mortality rate (hazard ratio [HR], 1.98; 95% confidence interval [95% CI], 1.30–3.03), and the second-highest group (5.6–6.8) had an increased risk of major cardiovascular disease events (HR, 1.67; 95% CI, 1.22–2.28) and infectious events (HR, 1.59; 95% CI, 1.04–2.45). Conclusion Elevated BUN/Cr ratios were associated with increased risks of infectious events, cardiovascular events, and all-cause mortality in patients undergoing hemodialysis.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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