인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract Background Autism spectrum disorder (ASD) is a worldwide concern that affects 75 million people globally. ASD is characterized by neurological abnormalities that include impaired social interactions, stereotyped patterns of behavior, and cognitive difficulties. Numerous studies have focused on acetylcholine (ACh), which plays a significant role in modulating neuronal and immunological function via acting on muscarinic and nicotinic receptors. The α7-nicotinic acetylcholine receptors (α7nAChRs) are a key subtype of ACh receptors that directly activate to influence neuroprotective actions. Furthermore, it is a relatively recent hypothesis that α7nAChRs may indirectly influence neuronal behavior by regulating oxidative stress, inflammation, and apoptosis, which is becoming increasingly prevalent. Main text This review aims to provide a comprehensive overview of drugs and herbs promising to treat autism. Furthermore, great concern for the evidence suggesting that activation of α7nAChRs through some drugs or herbal medicine may impact brain function and clarify underlying molecular mechanisms, including oxidative stress, inflammation, and apoptosis. The review also discusses the challenges in targeting α7nAChR and its implications for medication development and prospective avenues for further investigation. Conclusion ASD is a substantial global issue due to the annual rise in case numbers; therefore, additional study is essential to identify effective therapeutic strategies targeting various pathways, including α7nAChRs.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
최근 본 자료 전체보기
