인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
This study was conducted to investigate the effects of dietary cerium oxide nanoparticles (CeO 2 ‐NPs), on growth performance, plasma biochemistry and histopathological changes of koi fish ( Cyprinus carpio koi) exposed to florfenicol (FF) antibiotic in a 60‐day experiment. The fish with an average weight of 2.38 ± 0.44 g were completely randomly distributed into six different groups with three replications. The experimental groups included: Basal diet without additives (control), basal diet + oral antibiotic, basal diet + antibiotic bath, basal diet supplemented with CeO 2 ‐NPs, basal diet supplemnted with CeO 2 ‐NPs + antibiotic bath, and basal diet supplemented with CeO 2 ‐NPs + oral antibiotic. The experimental unit was a glass aquarium with a capacity of 110 L of water and 10 fish were stocked in it. At the end of the experimental period, growth performance of fish, blood plasma indices, and histopathology of liver, kidney, gill, and intestine were investigated. The results showed that the final body length of the fish in the basal diet + antibiotic bath group was significantly higher than the control group and the basal diet supplemented with CeO 2 ‐NP + oral antibiotic group ( p < 0.05). Histological studies showed that the kidney, liver, and intestinal lesions of fish in different groups did not differ microscopically. In gill tissues, changes in secondary lamellae and their destruction occurred in different parts of the primary lamellae in different groups, but overall, no differences were observed among the different groups. The plasma aspartate transaminase (AST) and alanine transaminase (ALT) levels were significantly decreased in all groups compared to the control ( p < 0.05), except the basal diet supplemented with CeO 2 ‐NPs + antibiotic bath group. The plasma blood urea nitrogen (BUN) level decreased significantly in the basal diet supplemented with CeO 2 ‐NPs + antibiotic bath group compared to the control, while this value increased in the basal diet + oral antibiotic and the basal diet supplemented with CeO 2 ‐NPs + oral antibiotic groups compared to the control ( p < 0.05). The results of this study revealed that adding CeO 2 ‐NPs to the basal diet at level of 0.8 mg/kg decreased the alkaline phosphatase (ALP), AST, and ALP levels in plasma of koi fish compared to the control ( p < 0.05). The simultaneous administration of dietary CeO 2 ‐NPs with the bath and oral FF antibiotic increased the AST and ALT levels and the BUN level in plasma, respectively ( p < 0.05).
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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