인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract Obesity results from various factors, such as menopause, age, physical activity, genetics, and environmental factors. Notably, the risk of obesity in women, especially in the context of menopause, has increased with rising life expectancy. Therefore, preventing and treating menopause-related obesity is crucial. Rice bran, the brown outer layer of the rice kernel, is known to contain nutrients and bioactive compounds. Rice bran supplement (RBS), a byproduct of rice polishing, recognizably treats obesity; moreover, it is also known to increase mitochondrial function. To validate the effect of RBS on menopause-induced obesity, we administered RBS to ovariectomized mice as a menopause model. Ultimately, we aimed to evaluate the potential of RBS as an alternative candidate to hormone replacement therapy for treating menopause-induced obesity. RBS treatment significantly reduced body weight by 20% and retroperitoneal fat by 97% compared to the HFD group. Furthermore, mitochondrial enzyme activities as mitochondrial respiratory function in the brain increased on average by 102% compared to the HFD group and by average by 93% compared to the ND group, highlighting the therapeutic efficacy of RBS in ameliorating metabolic complications associated with menopause, without the use of hormone replacement therapy.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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