인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
The escalating global health crisis due to antibiotic and antifungal resistance necessitates discovering novel antimicrobial agents. Extreme environment microorganisms, like those in mangrove soil, offer promising bioactive secondary metabolites. This study investigated the antibacterial and antifungal potential of Bacillus sp. RM10, an isolate from Ngurah Rai Mangrove Forest soil, via ethyl acetate extraction. Bacillus sp. RM10 was fermented in 100 mL ISP-2 liquid medium for 7 days. The supernatant was extracted twice with 100 mL ethyl acetate (1:1 v/v), and the extract was evaporated at 40°C. The viscous extract was tested against four bacteria ( Staphylococcus aureus ATCC 25923, Klebsiella pneumoniae ATCC 70060, Escherichia coli ATCC 25922, and Streptococcus mutans FNCC 0405) and two fungi ( Candida albicans and Aspergillus flavus ) using the Kirby-Bauer method. Results showed the ethyl acetate extract inhibited all tested microorganisms. Strong antibacterial activity was observed against S. aureus (15.00±1.30 mm), K. pneumoniae (14.50±0.90 mm), and E. coli (14.10±1.95 mm). Moderate inhibition was noted against S. mutans (9.00±1.43 mm). Strong antifungal activity was evident against C. albicans (10.50±1.40 mm) and A. flavus (10.80±0.60 mm). These findings confirm Bacillus sp. RM10 as a potential source of novel antibacterial and antifungal compounds, highlighting the therapeutic potential of mangrove ecosystems.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
최근 본 자료 전체보기
