인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Papaya ( Carica papaya ) and pulai ( Alstonia scholaris ) are recognized for their antihypercholesterolemic and antioxidant effects with minimal side effects. An equal combination of their leaf extracts demonstrated a synergistic effect as an HMG-CoA inhibitor, comparable to that of lovastatin in vitro . This study evaluated cholesterol levels and lipid peroxidation inhibition in a hypercholesterolemic animal model induced by a high-fat, high-cholesterol diet and propylthiouracil treatment. Sprague- Dawley rats were divided into three groups: Normal, Hypercholesterolemia, and Extract groups, which were subjected to treatment protocols over six weeks. The combination extracts (200:200 mg/kg BW) were administered and blood samples were analyzed for cholesterol and malondialdehyde levels. The results showed that hypercholesterolemia induction increased blood cholesterol to 173.72±5.6 mg/dL and MDA level to 19,44±4,59 nmol/mL. The extract treatment effectively decreased blood cholesterol levels by 27% and prevented lipid peroxidation, as shown by a 52% reduction in MDA levels (p<0.05).
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.