인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Excess fat in the visceral area in the form of obesity is associated with metabolic syndrome. Various factors have been identified that contribute to the pathophysiology of obesity-related metabolic diseases, including chronic inflammatory factors and immune system activation. One of the components of the immune and inflammatory system is CC-chemokine ligand 2 (CCL2), which is secreted by adipose cells. This study aimed to analyze the role of CCL2 by comparing the serum CCL2 levels between obese and non-obese subjects at Warmadewa University. Employing a cross-sectional design, sixty participants were selected through consecutive sampling and assessed for body weight, height, and serum CCL2 levels using the ELISA method. Data were analysed using the independent t-test. The p-value <0.05 was significant. This study indicated that serum CCL2 levels were significantly lower in obese individuals, measuring 111.57 ± 33.51 pg/mL, compared to 133.44 ± 44.91 pg/mL in individuals with normal weight. This difference was statistically significant, with a p-value of 0.0370. CCL2 levels in normal subjects were found to be higher than in obese subjects, suggesting a possible alteration in chemokine regulation associated with obesity. Further studies are needed to explore the underlying mechanisms.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.