인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract Background Transperineal prostate biopsy (TPPBx) under local anaesthesia (LA) has gained momentum in recent years. It is a simple, alternative office procedure to transrectal biopsy of prostate, with higher cancer detection and lower infection rates. This is the first reported transperineal biopsy in Malaysia using PrecisionPoint. We aim to determine clinically significant prostate cancer with TPPBx and its associated complication utilizing this method of biopsy. Methods We retrospectively reviewed medical records of patients who underwent TPPBx between November 2020 and September 2022. Electronic medical system was utilized to review patients’ information, PSA results, mpMRI reports (prostate volume, PI-RADS scoring) and complications experienced. Data were analysed to determine clinically significant prostate cancer (biopsy result with International Society of Urological Pathology (ISUP) grade 2 and above). Local anaesthesia was given through perineal skin infiltration as well as periprostatic nerve block. We performed our procedure using transrectal linear probe with biplane transducer for visual guidance using cognitive fusion. Biopsies were done in accordance with Ginsburg protocol. Ethics approval was obtained from University of Malaya Research Ethics Committee (UMREC) Results Total of 65 patients underwent transperineal biopsy under local anaesthesia from November 2020 to May 2022. All patients had mpMRI prior to the procedure. Prostate cancer was detected in 32 (49.2%) patients regardless of whether they had a previously negative transrectal prostate biopsy. Of the 65 patients, 27 (41.5%) were diagnosed with clinically significant prostate cancer requiring active treatment. The number of patients with clinically significant cancer was highest in the mpMRI reported PI-RADS 5 group with 15 patients (51.7%), followed by PI-RADS 4 group, with 10 patients (38.5%) and the PI-RADS 3 group, with two patients (20%). Complications reported were haematuria (33.8%) and acute urinary retention (6%). There were no reported urinary tract infections or sepsis as well as rectal bleeding after freehand transperineal biopsy of prostate. Conclusion Freehand transperineal biopsy of prostate using PrecisionPoint demonstrated an acceptable cancer detection yield while avoiding significant infection.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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