인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Background: Oral cavity cancer (OCC) is increasing in prevalence in younger patients without a history of tobacco or alcohol use. Emerging evidence suggests that chronic inflammation and intraoral metal allergies, such as those related to dental amalgam, may play a role in OCC pathogenesis, particularly in risk-factor negative populations. Objectives: (1) To determine the incidence of dental amalgam and metal allergies in OCC patients with and without traditional risk factors and, (2) To determine if there is an association between dental amalgam, allergies, and OCC laterality. Materials and Methods: Prospective cohort study from February 11, 2021 to May 31, 2023. Patients with OCC were tested for contact allergies to 45 metals found in dental amalgam. Patient demographics, OCC tumor characteristics, risk factors, presence of dental amalgam, and results from allergy testing were collected via chart review. Associations between metal allergies, dental amalgam, and OCC laterality were determined. Results: A total of 38 OCC patients underwent metal allergy testing and were included. Eighteen patients had a positive metal allergy, 90% of whom were female. Thirty (79%) patients had dental amalgam. Regardless of metal allergy status, patients with unilateral dental amalgam were significantly more likely to have an adjacent OCC ( p = 0.006). Conclusions: Metal allergies are more prevalent in women with OCC. Regardless of metal allergy status, the presence of dental amalgam appears to be associated with an increased risk of the development of an adjacent OCC.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.