인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Acinetobacter baumannii intracranial infection is a significant problem affecting the prognosis of neurosurgical patients. This study aimed to analyze the clinical characteristics and identify prognostic factors for in-hospital mortality in patients with post-neurosurgical A. baumannii intracranial infections. We retrospectively analyzed clinical data from 109 patients diagnosed with A. baumannii intracranial infection following neurosurgery between January 2015 and December 2022. A nomogram predicting in-hospital mortality was developed using logistic regression and validated through receiver operating characteristic(ROC) analysis. A total of 109 patients were included in this study, with an in-hospital mortality rate of 58.7%. Among the A. baumannii strains isolated from cerebrospinal fluid(CSF) cultures, 95.4% exhibited carbapenem resistance. Multivariate analysis identified CSF protein level (OR = 1.132, 95% CI = 1.039–1.233), A. baumannii bloodstream infection (OR = 8.9, 95% CI = 1.536–51.559), length of stay(OR = 0.946, 95% CI = 0.919–0.974), sex(male)(OR = 0.263, 95% CI = 0.077–0.894), platelet count (OR = 0.996, 95% CI = 0.992–0.999), and albumin level (OR = 0.896, 95% CI = 0.818–0.982) as independent factors associated with in-hospital mortality. A nomogram incorporating these factors achieved an area under the curve(AUC) of 0.879 (95% CI = 0.806–0.952). Post-neurosurgical intracranial infection with A. baumannii is associated with a high in-hospital mortality rate. Our study identified several independent prognostic factors, including CSF protein level, A. baumannii bloodstream infection, length of stay, sex(male), platelet count, and albumin level. These findings highlight the need for early identification and targeted interventions to improve patient outcomes.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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