인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract Background Metabolic syndrome (MetS) is a common metabolic and endocrine disease, and many studies have found that thyroid disorders, both overt and subclinical, might be accompanied by the risk of MetS. Objectives Assessment of indices of sensitivity to thyroid hormones (TH) in euthyroid patients with MetS, and correlation with components of MetS. Patients and methods This cross-sectional study included 240 euthyroid patients with metabolic syndrome living in New Damietta City. The study was conducted from April 2023 to April 2024. Patients were evaluated regarding age, sex, comorbidities, anthropometric measurements, blood pressure, and insulin resistance (IR) using Homeostatic Model Assessment for IR (HOMA-IR), lipid and thyroid profiles. Then, indices of sensitivity to TH were calculated that included thyroid-stimulating hormone index (TSHI), thyroid-stimulating hormone thyroxine resistance index (TT4RI), thyroid feedback quantile-based index (TFQI), parametric thyroid feedback quantile-based index (PTFQI), and the ratio of free tri-iodothyronine to free thyroxine (FT3/FT4). Results Indices of thyroid hormone sensitivity were higher among patients with MetS. The risk factors of MetS were obesity accounted for (92.1%), DM (77.5%), female gender (75%), and HTN (56.2%). All components of MetS, including increased age, female gender, HTN, DM, elevated BMI, WHR, TC, TG, LDL, and reduced HDL were associated with all indicators of sensitivity to thyroid hormones. Conclusion The study demonstrated a significant relationship between indices of thyroid hormone sensitivity and MetS and its risk factors.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.