인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
The COVID-19 pandemic has highlighted significant sex-based disparities in mortality, with men often experiencing higher death rates than women. These disparities vary across regions, time, COVID-19 waves, and viral variants (e.g., Alpha, Delta, Omicron). This study aims to analyze sex-specific mortality trends across pandemic waves and COVID-19 related mortality determinants using reverse transcriptase polymerase chain reaction (RT-PCR) confirmed cases. This retrospective cohort study was conducted on a data registry consisting of 44,544 hospitalized COVID-19 patients with positive RT-PCR from 2019 to 2021. Using SPSS version 26, a multiple logistic regression model with adjustment for potential confounders was conducted to calculate the odds ratio (OR) and 95% confidence interval (95%CI) of COVID-19 related death in each variable, both in the total population and separately sorted by sex. A dose-responsive relationship between age, number of comorbidities, and death was observed in the multiple logistic regression model. Certain comorbidities such as diabetes, cancer, cardiac diseases, chronic neurological diseases, and COPD were significantly associated with death. Males were at 17% higher risk of death compared to women (OR: 1.17, 95%CI: 1.09-1.25, P < 0.001) after adjustment for confounders. Compared to the fifth peak, females had 2.35 (95%CI: 1.91-2.89), 1.34 (95%CI: 1.17-1.53), 1.08 (95%CI: 0.95-1.23), and 0.76 (95%CI: 0.65-0.89) times odds of death, whereas males had 2.50 (95%CI: 2.07-3.01), 1.20 (95%CI: 1.05-1.37), 0.98 (95%CI: 0.86-1.12), and 0.78 (95%CI: 0.66-0.91) folds odds of death in the first, second, third, and fourth peaks, respectively. Our results showed that men had higher odds of mortality overall, but there were no significant differences at each peak separately. Also, age and the number of comorbidities demonstrated a significant association with mortality, with possible dose-responsive behavior.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
최근 본 자료 전체보기
