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Royal Society of Chemistry (RSC) RSC Advances 15(50)
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    초록·키워드

    Antibiotic contamination in water resources threatens ecosystems and public health, demanding sensitive and practical monitoring methods. We present an electrochemical sensor based on indium selenide (InSe) quantum dots integrated with mesoporous tantalum pentoxide (Ta<sub>2</sub>O<sub>5</sub>), forming a synergistic nanostructure with high electrocatalytic activity. The platform enables ultrasensitive detection of antibiotics such as tetracycline, ciprofloxacin, and amoxicillin, achieving a detection limit of ∼2.5 × 10<sup>-11</sup> M. The large surface area of Ta<sub>2</sub>O<sub>5</sub> facilitates analyte diffusion, while InSe QDs enhance charge transfer, together ensuring excellent sensitivity, selectivity, and reproducibility (RSD <2%). The sensor retains stability over 30 days and demonstrates recovery rates above 92% in tap, river, and wastewater samples. Offering simplicity and low cost compared to conventional analytical methods, this nanocomposite electrode provides a robust and scalable solution for real-time environmental monitoring of antibiotic pollutants.

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