인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract Background Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm arising outside the bone marrow, most commonly in the head and neck region. EMP involving the pectoralis major muscle is exceptionally rare, and progression to multiple myeloma may occur even without initial bone marrow involvement. Case presentation A 76-year-old male presented with a 2-month history of a right anterior chest mass, mild stabbing pain, and 3-kg weight loss. Imaging revealed a 46 × 47 × 45 mm soft tissue lesion in the right parasternal region involving the pectoralis major muscle without bone involvement. Incisional biopsy demonstrated malignant plasma cells with lambda light chain restriction, Ki67 45%, MUM1 and c-MYC positivity. The patient underwent radical external radiotherapy (40 Gy/20 fractions) with no immediate complications. Follow-up revealed elevated monoclonal proteins and, at 7 months, cranial MRI showed multiple lytic and blastic lesions. Multiple myeloma was confirmed by serum protein electrophoresis and multiparametric flow cytometry. The patient received chemoimmunotherapy with daratumumab, bortezomib, and dexamethasone, followed by lenalidomide maintenance. At the 13-month follow-up, the patient remained asymptomatic. Conclusion EMP of the pectoralis major muscle is extremely rare. Accurate diagnosis requires biopsy, immunohistochemistry, and close follow-up. Local radiotherapy is effective for solitary EMP, but systemic therapy is necessary if progression to multiple myeloma occurs. This case highlights the importance of multidisciplinary management and long-term surveillance.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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