인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
The present study focused on developing nanocrystalline hydroxyapatite (NHAP) from waste eggshells and assessed its role in bone regeneration after tooth extraction, with and without the addition of zinc oxide nanoparticles (ZnO NPs). Sixty adult male albino rats were used. The lower first molar was extracted, and the rats were divided into four groups (n = 15): Group I, control without treatment; Group II, bone socket loaded with ZnO NPs; Group III, bone socket loaded with NHAP; and Group IV, bone socket treated with both ZnO NPs and NHAP. Animal scarification was performed 4 weeks after extraction, and the results were assessed using histological, histomorphometric, and scanning electron microscopic assessment of bone. Also, energy dispersive X-ray analysis (EDXA) was performed for all animal groups and subsequently evaluated statistically. After 4 weeks of extraction, Group I exhibited complete healing with remnants of immature bone, while in Groups II and III, mature compact bone filled most of the socket, and cancellous bone occupied small areas. Group IV exhibited complete healing of the extraction socket, which was completely closed by mature bone. The combined use of NHAP derived sustainably from eggshells and laboratory-synthesized ZnO NPs proposes a potential, biocompatible, and economical approach for improving alveolar socket healing. These nanomaterials enhance osteoinduction and antibacterial properties and exemplify a novel application of locally obtained waste and cost-effective synthesis methods, rendering them highly appropriate for clinical utilization in resource-constrained environments, as in developing countries. Thus, dentists can access and benefit from state-of-the-art nanotechnological solutions without financial impediments, as in alveolar ridge preservation and rapid healing after extraction for future implant placement. Treatment modalities with ZnO NPs and NHAP administered separately could accelerate bone socket healing. However, combining ZnO NPs and NHAP resulted in a more rapid improvement of the histological and statistical results. This might be due to the enhancement of the early release of growth factors that increase angiogenesis and regeneration in healing sockets. However, additional studies are needed to evaluate this combination.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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