인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract Malnutrition, specifically protein-energy malnutrition, significantly impairs growth and overall health, marked by deficiencies in serum protein, haemoglobin, and insulin-like growth factor-1 (IGF-1). Chicken eggshell (CE) powder, a rich source of bioactive nutrients, remains underutilised despite its high mineral and protein content. To evaluate the efficacy of CE powder supplementation on biomarkers associated with nutritional status—serum protein, haemoglobin, IGF-1, haematocrit, erythrocytes, and retinol-binding protein (RBP) in malnourished rats fed a protein-restricted diet. Thirty male rats (Rattus norvegicus), initially malnourished through a low-protein diet (4% wt/wt protein Body Weight (BW)) for 4 weeks, were divided into three groups: a control group (normal protein diet, 23% wt/wt protein), a low-dose CE group (100 mg/kg BW), and a high-dose CE group (200 mg/kg BW). Supplementation lasted another 4 weeks, after which blood biomarkers and body weight changes were analysed using ELISA and statistical analyses (ANOVA and paired t-tests). Administration of CE powder significantly increased haemoglobin and IGF-1 levels, particularly at the higher dosage (200 mg/kg BW; p < .0001). Both doses (100 mg/kg BW and 200 mg/kg BW) similarly enhanced haematocrit and erythrocyte levels compared to the control group (p = .0513). RBP was significantly elevated with the higher dose compared to the lower dose (p < .0001). Serum protein levels increased dose-dependently, although without statistical significance between dosages. Body weight increased across all groups, with significant weight gain in the high-dose group (p = .048). CE powder supplementation notably improves critical biomarkers related to malnutrition, especially at a dosage of 200 mg/kg BW, indicating its potential as a cost-effective and sustainable nutraceutical strategy for addressing malnutrition and protein deficiencies.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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