인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
The purpose of this cross-sectional study was to determine the effect of at-risk drinking on central hemodynamics and aortic stiffness in midlife adults. A total of 38 midlife men and 41 postmenopausal women, aged 50-64 and free of major clinical diseases, were included. Based on USAUDIT-C scores derived from the U.S. Alcohol Use Disorder Identification Test, participants were classified as low-risk drinkers (n = 50) or at-risk drinkers (n = 29). Central blood pressure (BP), aortic wave reflection indices, as well as carotid-to-femoral pulse wave velocity (cfPWV; a measure of aortic stiffness) were measured. Regardless of sex (p = 0.11 for both), among participants free of antihypertensive medications (n = 51), at-risk drinkers had higher central systolic (p = 0.002) and diastolic BP (p < 0.001) compared with low-risk drinkers, while there was no between-group difference in central BP among treated participants (n = 28; p ≥ 0.41). Among untreated participants, higher USAUDIT-C scores remained independently associated with elevated systolic (p < 0.001) and diastolic BP (p = 0.003), after controlling for wave reflection indices and cfPWV. Regardless of antihypertensive medication use (p ≥ 0.25) and sex (p ≥ 0.10), no between-group differences were observed in aortic wave reflection indices (p ≥ 0.18) and cfPWV (p = 0.16). These findings suggest that elevated central BP associated with at-risk drinking is related to mechanisms other than enhanced aortic wave reflection or aortic stiffening.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.