인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract There are various studies in the past which have analyzed quality of life and survival data; among them, many studies have highlighted the assessment of quality of life in a short time within a year, but very few studies have stressed the factors affecting this quality of life in operated head and neck cancer patients in the Indian subpopulation. Material and methods This prospectively designed study was conducted for 2 years with 88 of 124 patients completing the quality-of-life questionnaire. We utilized the European Organisation for Research and Treatment of Cancer (EORTC 30) quality-of-life questionnaire (QLQ) along with (EORTC-HN-35) prior to surgery (T0) and at 6-month (T1) and 12-month (84 patients) follow-up periods (T2). Variations in quality of life at these three time points were analyzed. Predictive factors like age, sex, comorbidity, location of tumor, tumor recurrence, stage of tumor, effect of radiotherapy, and type of flap used for reconstruction on QoL scores at 6 months after surgery were evaluated. Results Overall QoL scores showed no drop throughout the study period. However, patients experienced significant declines in social interactions, role function, and cognitive function following treatment. The pain domain of general symptoms showed notable improvement. Social eating, social contact, teeth problems, and speech demonstrated significant worsening at the 6-month assessment but remained steady between the 6- and 12-month evaluations. Symptoms like mouth opening, senses, swallowing function, dry mouth, and sticky saliva showed continuous deterioration until the first postoperative year. The primary determinants affecting QoL outcomes 6 months post-treatment were tumor characteristics like radiation therapy administration, lymph nodal involvement, and stage of malignancy. Conclusions Following extensive head and neck surgical procedures, patients maintained quality-of-life scores. EORTC questionnaire facilitates deeper understanding of the complex physical, psychological, and social challenges faced by our patients, thereby improving focused therapeutic interventions and reaching the fundamental aim of improving quality of life.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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