인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Pseudomonas aeruginosa is a major contaminant in cosmetics, posing significant health risks to consumers. These bacteria form biofilms that protect them from disinfectants commonly used in the cosmetic industry. This study aimed to assess the impact of disinfectants, cleaners, and sanitizers on the metabolic activity and biofilm formation of P. aeruginosa isolated from the production line in a cosmetic manufacturer. In vitro experiments were conducted using silicone, Teflon, ethylene propylene diene monomer and acid-resistant steel surfaces, which are commonly used materials in cosmetic production line equipment. Spectrophotometric methods were used to evaluate biofilm formation and metabolic activity, while different imaging techniques (SEM, EFM, OCT) were employed to visualize biofilm structure directly on examined surfaces. The results showed that hypochlorous acid is the most effective disinfectant in inhibiting biofilm formation. Hypochlorous acid significantly reduced the metabolic activity of P. aeruginosa, particularly in biofilms forming on the surface made of stainless steel. Additionally, the study validated the feasibility of implementing a sterilization method using hypochlorous acid directly in industrial conditions for production line sterilization. Results showed a significant reduction in contamination levels in water passing through the installation, from an uncountable level to below 0.1 × 10<sup>1</sup> CFU mL<sup>-1</sup>. In conclusion, the effectiveness of disinfectants in preventing biofilm formation and metabolic activity is dependent on their composition and the type of surface on which the biofilms form. Hypochlorous acid proves to be an effective disinfectant for combating bacterial biofilms in the cosmetic industry. KEY POINTS: The tested strains of P. aeruginosa formed a strong biofilm and were drug-resistant Hypochlorous acid exhibited the highest antibacterial efficacy among the tested agents Hypochlorous acid effectively eliminated biofilm-associated microbes in the facility's water system.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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