인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Pyoderma gangrenosum (PG) is a rare non-infectious neutrophilic dermatosis which is characterized by a rapidly progressive, painful ulcer. Bilateral manifestation of PG is exceptionally rare and can easily be misdiagnosed as infection or vascular ulceration, delaying proper treatment. A 76-year-old woman presented with painful, crusted ulcers on her bilateral lower legs that developed over 2 weeks. Initially, the lesions erupted as erythematous papules that enlarged rapidly and ulcerated. There was no history of trauma, systemic illness, or prior ulceration. Laboratory tests revealed mild anemia and an elevated C-reactive protein level. Swab culture from the wound site showed growth of <i>Pseudomonas aeruginosa</i>. There was no response to antibiotics, suggesting a non-infective etiology. An incisional skin biopsy revealed dense neutrophilic infiltrate with dermal necrosis in the absence of vasculitis or infection, findings characteristic of neutrophilic dermatosis and consistent with PG. The patient was treated with oral prednisolone and local saline dressings, resulting in significant improvement within 2 weeks and complete healing without recurrence. PG can occur even in the absence of systemic diseases and may mimic infectious or vascular ulcers. Awareness about atypical presentations, early biopsy and timely initiation of corticosteroid therapy is essential to avoid misdiagnosis and achieve favorable outcomes.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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