인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
Abstract Background Malignant pleural effusion (MPE) is a frequent and debilitating complication of advanced malignancy, often resulting in significant morbidity and impaired quality of life. The optimal approach for durable pleural control and symptom relief remains debated. This randomized controlled trial compared the efficacy and clinical outcomes of video-assisted thoracoscopic surgery (VATS) pleurodesis versus conventional thoracostomy tube drainage with chemical pleurodesis in patients with MPE. A total of 100 patients with a confirmed MPE diagnosis were randomized equally into two groups ( n = 50 each): VATS pleurodesis and thoracostomy tube drainage with bleomycin pleurodesis. The primary endpoint was successful pleurodesis (complete response) after 30 days. Secondary outcomes included hospital stay, pain score, postoperative performance status, and complications. Results VATS achieved a significantly higher pleurodesis success rate (90% vs 72%; p = 0.022) and better postoperative performance status (ECOG I: 50% vs. 10%; p < 0.001). Median hospital stay was shorter in the VATS group (4 vs. 7.5 days; p < 0.001), and postoperative pain scores were lower ( p = 0.039). Both interventions improved dyspnea scores significantly ( p < 0.001). No significant differences were observed in ICU admission (36% vs 38%; p > 0.05) or complication rates. Conclusions VATS pleurodesis using mechanical abrasion and/or electrocautery provides superior short-term outcomes compared with thoracostomy tube drainage with bleomycin pleurodesis for malignant pleural effusion, offering higher treatment success, improved functional recovery, reduced postoperative pain, and shorter hospitalization without added morbidity.
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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