인문학
사회과학
자연과학
공학
의약학
농수해양학
예술체육학
복합학
DBpia AI
AI 에이전트
AI 아이디어
AI 리더
AI 뷰어
Citeasy
크롬 서지관리 다운로드
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록·키워드
This randomized clinical trial was designed to evaluate whether glycolic acid (GA) is non-inferior to ethylenediaminetetraacetic acid (EDTA) regarding postoperative pain after endodontic treatment. A total of 240 patients requiring treatment were randomly assigned to four groups according to the irrigant (GA or EDTA) and the instrumentation technique (reciprocating or rotary). Postoperative pain was assessed using the numeric rating scale (NRS, 0–10) at 24 h, 48 h, and 7 days. A non-inferiority margin (Δ = 0.9) was prespecified as the maximum acceptable difference between GA and EDTA. Non-inferiority was concluded if the upper bound of the one-sided 95% confidence interval (equivalent to the two-sided 90% CI) for the difference in means (GA – EDTA) was below Δ. Analgesic intake was also recorded. Postoperative pain peaked at 24 h and significantly decreased over time (p < 0.001). At all evaluated time points, the upper bound of the one-sided 95% confidence interval for the difference between GA and EDTA remained below Δ, demonstrating that GA was non-inferior to EDTA. Exploratory two-sided analyses revealed no significant differences in pain intensity between irrigants or instrumentation techniques (p > 0.05). Most patients reported absent or mild pain, and 79.2% did not require analgesics, with no significant difference among groups (p = 0.616). GA is non-inferior to EDTA in terms of postoperative pain following endodontic treatment, regardless of instrumentation technique. Both irrigants provided similar clinical outcomes, with low analgesic intake and favorable patient-centered results. Trial registration number. Brazilian Clinical Trials Registry (ReBec). Registration number RBR-44q9k6q. (Retrospectively registered: October 17, 2023).
인공지능 문자 인식 모델을 통해 추출된 텍스트로, 일부 오타나 오류가 포함될 수 있으나 지속적으로 개선 중입니다.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
오류를 발견하셨다면 해당 부분을 드래그한 후 ' 를 통해 신고해주세요.
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