Feasibility of laparoscopic cytoreduction in patients with localized recurrent epithelial ovarian cancer

백이선; 이유영; 김태중; 최철훈; 이정원; 김병기; 배덕수

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자료유형: 학술저널

저자정보: 백이선 (성균관의대 산부인과) 이유영 (삼성서울병원) 김태중 (삼성서울병원) 최철훈 (삼성서울병원) 이정원 (삼성서울병원) 김병기 (성균관대학교) 배덕수 (삼성서울병원)

저널정보: 대한부인종양학회 Journal of Gynecologic Oncology Journal of Gynecologic Oncology Vol.27 No.3

발행연도: 2016.1

수록면: 1 - 9 (9page)

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이 논문의 연구 히스토리 (3)

2019

Prediction of survival outcomes in patients with epithelial ovarian cancer using machine learning methods

백이선 , 이정원 , 박정열 외 7명 Journal of Gynecologic Oncology 2019.01 학술저널

2016

Feasibility of laparoscopic cytoreduction in patients with localized recurrent epithelial ovarian cancer

백이선 , 이유영 , 김태중 외 4명 Journal of Gynecologic Oncology 2016.01 학술저널

2015

Feasibility and outcomes of laparoscopic cytoreduction in patients with recurrent epithelial ovarian cancer

백이선 의학과 2015.01 학위논문

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Objective: To assess the feasibility of laparoscopic cytoreduction in patients with localizedrecurrent epithelial ovarian cancer (EOC) by comparing its outcomes to those of laparotomy. Methods: We performed retrospective analysis in 79 EOC patients who had a localized singlerecurrent site, as demonstrated by computed tomography (CT) scan, magnetic resonanceimaging, or positron emission tomography/CT scan; had no ascites; were disease-free for12 or more months prior; and who had undergone secondary cytoreduction (laparoscopyin 31 patients, laparotomy in 48 patients) at Samsung Medical Center between 2002 and2013. By reviewing the electronic medical records, we investigated the patients’ baselinecharacteristics, surgical characteristics, and surgical outcomes. Results: There were no statistically significant differences between laparoscopy andlaparotomy patients in terms of age, body mass index, cancer antigen 125 level, tumor type,initial stage, grade, recurrence site, type of procedures used in the secondary cytoreduction,adjuvant chemotherapy, and disease-free interval from the previous treatment. With regardsto surgical outcomes, reduced operating time, shorter hospital stay, and less estimated bloodloss were achieved in the laparoscopy group. Complete debulking was achieved in all cases inthe laparoscopy group. Conclusion: The laparoscopic approach is feasible without compromising morbidity andsurvival in selected groups of patients with recurrent EOC. The laparoscopic approach can bea possible treatment option for recurrent EOC.

참고문헌 (24)

참고문헌 신청

Ferlay J / 2010 / Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 / Int J Cancer 127:2893~2917

Bray F / 2012 / Global cancer transitions according to the Human Development Index (2008-2030): a population-based study / Lancet Oncol 13:790~801

Bristow RE / 2002 / Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a meta-analysis / J Clin Oncol 20:1248~1259

Ozols RF / 2003 / Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group study / J Clin Oncol 21:3194~3200

du Bois A / 2003 / A randomized clinical trial of cisplatin/paclitaxel versus carboplatin/paclitaxel as first-line treatment of ovarian cancer / J Natl Cancer Inst 95:1320~1329

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백이선

소속기관 성균관의대 산부인과

주요연구분야 의약학 > 임상의학 > 산부인과학

논문수 5 이용수 0

Yoo-Young Lee

소속기관 Sungkyunkwan University School of Medicine