개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
논문을 무제한 열람 이용할 수 있어요.
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Mitochondrial DNA mutations have been reported in recent years in association with sensorineural hering loss. The purpose of this study is to identify the association between the noise-induced sensorineural hearing loss and the A to G mutation at nucleotide 3243, 1555, 7445 of mitochondrial DNA. Study subjects were established by history and chart review, and audiological and clinical data were obtained. Blood was sampled from 214 normal controls, 102 noise-induced hearing loss, and 28 sensorineural hearing loss. The DNA of these individuals were extracted, and mitochondrial DNA fragments were analyzed by polymerase chain reaction. Subsequently, the coding sequence of mitochondrial DNA 3243, 1555, 7445 were sequenced, and compared to the normal sequence, and all sequence variations were analyzed by restriction enzymes. Mitochondrial DNA mutations (3243A→G, 1555A→G, 7445A→G) were not detected by polymerase chain reactions in any patients with noise-induced hearing loss, sensorineural hearing loss, and normal controls. The DNA sequencing of PCR products did not revealed an A to G substitution at nucleotide 3243, 1555, 7445 of mitochondrial DNA. The noise-induced sensorineural hearing loss was not associated with mitochondrial DNA mutation (3243A→G, 1555A→G, 7445A→G).
목차
Abstract
연구 대상 및 방법
연구 결과
고찰
감사의글
요약
참고문헌
참고문헌 (23)
참고문헌 신청
[학술지(정기간행물)] - / 2000 / Mitochondrial DNA A3243G mutation in noise-induced sensorineural hearing loss 12 (3) : 319 ~ 326
[학술지(정기간행물)] - / 1983 / Variability of noise- induced damage in the guinea pig cochlea electrophisiology and morphological correlates after strictly controlled exposure : 55 ~ 70
[학술지(정기간행물)] - / 1998 / Familial progressive sensorineural deafness is mainly due to the mtDNA A1555G mutation and is enhanced by treatment with aminoglycosides 62 : 27 ~ 35
[학술지(정기간행물)] - / 1996 / Genetics of age-related loss in mice Susceptibility of inbred and F1 hybrid strains to noise-induced hearing loss 93 : 181 ~ 187
[학술지(정기간행물)] - / 1990 / A mutation in the tRNALEU gene associated with the MELAS subgroup of mitochondrial encephalopathies : 651 ~ 348 653
[학술지(정기간행물)] - / 1983 / Variability of noise- induced damage in the guinea pig cochlea electrophisiology and morphological correlates after strictly controlled exposure : 55 ~ 70
[학술지(정기간행물)] - / 1998 / Familial progressive sensorineural deafness is mainly due to the mtDNA A1555G mutation and is enhanced by treatment with aminoglycosides 62 : 27 ~ 35
[학술지(정기간행물)] - / 1996 / Genetics of age-related loss in mice Susceptibility of inbred and F1 hybrid strains to noise-induced hearing loss 93 : 181 ~ 187
[학술지(정기간행물)] - / 1990 / A mutation in the tRNALEU gene associated with the MELAS subgroup of mitochondrial encephalopathies : 651 ~ 348 653
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Mitochondrial DNA mutation analysis in stomach cancer
한국동물학회 학술대회
1998 .01
-
Human Mitochondrial DNA Sequence variations in Korea Population
한국동물학회 학술대회
1998 .01
-
Mitochondrial DNA Mutation and Oxidative Stress
Interdisciplinary Bio Central
2011 .01
-
Nucleotide Sequence Variations in The Control Region of Human Mitochondrial DNA in Korean Population
한국동물학회 학술대회
1994 .01
-
Mitochondrial DNA Control Region Polymorphism in a Population from Korea
한국동물학회 학술대회
2000 .01
-
Analysis of Mitochondrial DNA Deletion in Human Cancers
한국동물학회 학술대회
1997 .01
-
Mitochondrial DNA Mutation Analysis Using Paraffin-embedded Muscle Tissues
한국동물학회 학술대회
2000 .01
-
Phylogenetic utilities of nuclear ribosomal DNA and mitochondrial DNA
한국동물학회 학술대회
1999 .01
-
The role of mitochondrial DNA mutation on neurodegenerative diseases
Experimental and Molecular Medicine
2015 .01
-
Association of ND4L gene 10609 mutation and hearing loss in a Korean with ESRD patients
대한임상검사과학회지
2012 .01
-
만성 신부전증 환자에서 미토콘드리아 활성과 청력손실과의 연관성
대한임상검사과학회지
2006 .01
-
Mitochondrial DNA D-loop sequences variation and evolution of Korean cattle, Hanwoo
한국동물학회 학술대회
1999 .01
-
DNA Polymerase 의 구조 및 기능 연구 - DNA 염기서열 결정에 응용 - ( Structural and Functional Aspects of DNA Polymerase - Applications to DNA Sequencing - )
생명과학
1993 .10
-
Detection of Mitochondrial DNA Mutations Using SSCP Analysis in Cheju Native Horses
한국동물학회 학술대회
1998 .01
-
Molecular cross talkamongthecomponentsofthe regulatory machinery of mitochondrial structure and quality control
Experimental and Molecular Medicine
2020 .01
-
Variations in Mitochondrial DNA of Pleurotus sajor-caju
한국균학회지
1994 .01
-
Phylogeny of Phellinus based on the restriction enzyme analysis of mitochondrial DNA.
한국동물학회 학술대회
1994 .01
-
The mitochondrial genome of Silkworm (Bombyx mori) : Complete DNA Sequence, Genome Organization, and Comparisons with Mitochondrial Genome of Other Insect.
한국동물학회 학술대회
1998 .01
-
Genetic Analyses of Mitochondrial DNA from Northeast Asian Peoples
한국유전체학회 Conference
2004 .01
-
Phylogenetic Relationships of Korean Salmonids Based on Mitochondrial DNA Control Region Sequences
한국동물학회 학술대회
1999 .01
이 논문의 저자 정보
이 논문과 함께 이용한 논문
Escherichia coli 에서 리보솜 조립과정에 관여하는 단백질들
최은실
,
황지환
생명과학회지
2014
.08
알츠하이머질환 모델동물인 Tg2576마우스의 행동, Aβ-42 침적, 신경성장인자 대사에 미치는 reserpine의 영향
고준
,
최선일
,
김지은
외 6명
생명과학회지
2013
.06
뇌신경세포에서 tPA에 의한 MMP의 발현 조절에 관한 연구
고운철
,
이선령
생명과학회지
2009
.06
파킨슨병모델 랫드 흑색질에서 이환기간에 따른 신경세포 변화에 관한 연구
유영복
Laboratory Animal Research
2003
.12
치매환자에서 transposable elements에 의한 유전자 발현조절의 생물정보 분석
김대수
,
허재원
,
하홍석
외 3명
생명과학회지
2006
.12
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-470-014448510