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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국생명과학회 생명과학회지 생명과학회지 제16권 제7호
발행연도
2006.12
수록면
1,071 - 1,079 (9page)

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The purpose of this study was to observe the effects of the feeding physiological activity substance in feral peach(Prunus persica Batsch var. davidiana Max.) extract intake on the improvement of the lipid compositions, apolipoprotein and blood pressure level in spontaneously hypertensive rats(SHR, Wistar strain, male) fed the experimental diets for 33 days. Concentrations of total cholesterol, triglyceride(TG), LDL-cholesterol, free cholesterol and atherosclerotic index in serum were significantly lower in the feral peach extract intake groups[groups 5 g% Ex.(basal diet+feral peach 5.0 g% extract), 10 g% Ex.(basal diet+feral peach 10.0 g% extaract)] than those in the group Control(basal diet+water). In the ratio of HDL-cholesterol concentration to total cholesterol and HDL-cholesterol concentration, feral peach 5.0 g%, 10.0 g% extract intake groups(group 5 g% Ex. and 10 g% Ex.) were higher percentage than in the group Control. However, concentrations of total cholesterol and TG in liver and brain were significantly lower in the groups 5 g% Ex. and 10 g% Ex. than those in the group Control. But the concentrations of apolipoprotein(Apo) A-I and Apo A-Ⅱ in serum were significantly higher in the feral peach 5.0 g% and 10.0g% extract intake groups(5 g% Ex. and 10 g% Ex.) than in the control group. However, concentrations of Apo C-Ⅱ, Apo C-Ⅲ, Apo E and ratio of Apo B to Apo A-I in serum were fairly reduced in the groups 5 g% Ex. and 10 g% Ex. than in the control group. The levels of systolic and diastolic blood pressure were significantly lower in feral peach 5 g% Ex. and 10 g% Ex. groups than control group. However, no significance was found in the effect of among the groups(groups 5 g% Ex. and 10 g% Ex.). From these results, physiological activity substance in feral peach(Prunus persica Batsch var. davidiana Max.) extracts were effective on the improvement of the lipid compositions and cardiovascular heart disease, hypertension in spontaneously hypertensive rats. And particularly, feral peach extracts were more effective as a therapeutic regimen for the control of blood pressure in hypertension.

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UCI(KEPA) : I410-ECN-0101-2009-470-017616807