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자료유형
학술저널
저자정보
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한국실험동물학회 Laboratory Animal Research Laboratory Animal Research Vol.22 No.1
발행연도
2006.3
수록면
19 - 23 (5page)

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It has been reported that the production of miniature animals contributes to the organ transplantation. Among many species, pig is the most fittable species to human in the point of comparative biology. However, the physiological and biochemical analysis were not conducted between miniature pigs and conventionally reared pigs. Thus, we analyzed whether there was a difference of physiological parameters between miniature pigs and conventionally bred pigs. The levels of respiratory frequency and heart rate were significantly not different between two groups. Total number of red blood cells (RBC), hematocrit, hemoglobin, erythrocyte sedimentation rate (ESR), mean corpuscular hematocrit (MCH), and mean corpuscular hematocrit concentration (MCHC) were higher in miniature pigs than in conventionally reared pigs. However, total number of white blood cells (WBC) and leukocyte differential counting were not different between two groups. In addition, the value of serum electrolytes was not different between two groups. In the experiment of serum biochemical analysis, albumin and uric acid were increased but blood urea nitrogen, triglyceride, and LDL-cholesterol were decreased in miniature pigs compared to conventionally reared pigs. The biochemical value and organ weight in this study may contribute to understanding of the physiological characteristics of miniature pigs.

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